Xiulei Mo Selected Research

Neoplasms (Cancer)

11/2023	A multiplexed time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting the SMAD4-SMAD3-DNA complex.
7/2023	A multiplexed time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting SMAD4-SMAD3-DNA complex.
9/2022	Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells.
1/2022	Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
1/2021	An expanded universe of cancer targets.
1/2021	Hypomorph mutation-directed small-molecule protein-protein interaction inducers to restore mutant SMAD4-suppressed TGF-β signaling.
1/2019	HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers.
12/2018	Large tumor suppressor 2, LATS2, activates JNK in a kinase-independent mechanism through ASK1.
2/2018	Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction.
1/2018	The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery.

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Xiulei Mo Research Topics

Disease

13	Neoplasms (Cancer) 11/2023 - 01/2017
1	COVID-19 01/2023
1	Ovarian Neoplasms (Ovarian Cancer) 09/2022
1	Lung Neoplasms (Lung Cancer) 01/2017

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2017
2	Transforming Growth Factor beta (TGF-beta)IBA 11/2023 - 07/2023
1	Serine Proteases (Serine Protease)IBA 01/2023
1	Taxoids (Taxanes)IBA 09/2022
1	taxaneIBA 09/2022
1	Biomarkers (Surrogate Marker)IBA 09/2022
1	Adhesives (Glues)IBA 01/2021
1	Ro 31-8220IBA 01/2021
1	Immunologic Factors (Immunomodulators)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 12/2018
1	Protein Isoforms (Isoforms)IBA 02/2018
1	MethyltransferasesIBA 02/2018
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	palbociclibIBA 01/2017

Therapy/Procedure

2	Immunotherapy 11/2023 - 07/2023
1	Precision Medicine 01/2022
1	Therapeutics 01/2021